Medicina e Morale. Rivista internazionale di Bioetica is a scientific quarterly journal promoted by the Università Cattolica del Sacro Cuore (UCSC). The Journal publishes original articles on bioethics, moral philosophy, medical ethics, deontology, philosophy of law, and related disciplines, as well as case studies in which ethical dilemmas are relevant. Started up by Catholic Doctors of Turin, with the aim of reflecting on medico-moral issues, the Journal published the first issue in 1951, under the direction of Fr. Agostino Gemelli (UCSC’s Rector), Peter Sisto (Professor of Special Pathology at the University of Turin) and Peter Swifts (Professor of Biological Chemistry at the University of Milan). Physicians Enzo De Lorenzi and Gian Pietro Ravera worked as Editorial Staff. From No. 1 in 1955 “Vita e Pensiero” publisher bought the Journal, but Editor-in-Chief and Editor Staff were unchanged. In 1973 the above-mentioned publisher tried to implement the Journal through a major involvement of the Faculty of Medicine. Prof. Angelo Fiori, forensic scientist, became the Editor-in-chief and the Editorial Committee and the Editorial Staff were enlarged. In 1974 Prof. Elio Sgreccia started to collaborate with the Journal, and later he became Editor, alongside Prof. Fiori. The Journal broadened its horizon, dealing with Bioethics. After some administrative difficulties in 1983, “Medicina e Morale”, managed by the Faculty of Medicine at UCSC, came quickly to the milestone of over 3000 subscribers, partly from foreign countries. In December 2015, the Rector of UCSC issued a decree on the journal "Medicina and Morale. Rivista internazionale di Bioetica”, which, together with the Code of ethics previously published, outlines the new structure, defining in more detail the scope and the role of the different organs. Prof. Antonio G. Spagnolo, director of the Institute of Bioethics and Medical Humanities of the UCSC, has been appointed as director. We can say with justifiable satisfaction, that now the Journal has credit in Italy and in other countries around the world and it is present in several important Universities and Cultural Institutions.